Healthtech startups in San Francisco

Jane Chao & Xingjuan Chao

Neurotech/medtech company (founded 2014) making a rapid, portable EEG headband plus AI ('Clarity') that detects seizures and status epilepticus at the bedside. Completed an upsized ~$207M Nasdaq IPO (CBLL) i...

Jeff Huber (founding CEO)

Founded 2016 (spun out of Illumina); maker of the Galleri multi-cancer early-detection (MCED) blood test that screens for signals across 50+ cancers. Divested from Illumina and now an independent public comp...

Andrew Dudum, Hilary Coles, Jack Abraham

Founded 2017; a direct-to-consumer digital-health platform connecting patients to licensed providers and personalized treatments across sexual health, weight loss, dermatology and mental health. Publicly tra...

Frederic Moll, Robert Younge, John Freund

Founded 1995; the pioneer and global leader of robotic-assisted minimally invasive surgery via the da Vinci Surgical System (and Ion for lung biopsy). Publicly traded (Nasdaq: ISRG); one of the largest pure-...

Othman Laraki, Elad Gil, Nish Bhat, Taylor Sittler

Founded 2015 as Color Genomics; a population-health platform spanning genetic testing, cancer risk screening and virtual care, plus an AI 'Copilot' for oncology built with OpenAI (2024). Scaled national COVI...

Gabriel Otte, Charlie Roberts, Riley Ennis

Founded 2014; a multiomics liquid-biopsy company using machine learning on blood-based genomic, protein and methylation signals for early cancer detection (lead: colorectal cancer screening). Raised $254M in...

Owen Tripp (merger of Grand Rounds + Doctor On Demand)

Formed 2021 via the Grand Rounds/Doctor On Demand merger (later + Included Health); an integrated virtual-care and care-navigation platform for employers and health plans spanning primary care, behavioral he...

Elon Musk & founding team

Founded 2016; developing implantable brain-computer interfaces (the N1 implant + R1 surgical robot) to restore movement/communication, with first human implants in 2024. Maintains a large Fremont operation a...

Kate Rosenbluth & Deanna Harshbarger (Stanford science)

Bioelectronic neurotech medtech company (founded 2013) whose wrist-worn Cala kIQ delivers transcutaneous afferent patterned stimulation (TAPS) to reduce hand tremor in essential tremor and Parkinson's. Close...

Eren Bali & Caesar Djavaherian

Founded 2015 by Udemy co-founder Eren Bali; a tech-enabled hybrid primary/urgent-care provider with an AI-assisted EHR and a national clinic network. Well-funded private; expanded AI charting in 2024.

Kara Egan & Avnesh Thakor

Femtech company developing the Teal Wand, an at-home self-collection device for cervical cancer (HPV) screening that received FDA clearance in 2025. Aims to expand access beyond in-clinic Pap smears. Venture...

AI clinical documentation & coding

Founded 2020 by Nikhil Buduma and Mike Ng. AI documentation and medical-coding platform for health systems. Closed a $243M Series C in July 2025 (Oak HC/FT, a16z) at a $1.25B valuation, reaching unicorn stat...