AI startups in Toronto

Dr. Alexander Dobranowski (CEO)

Toronto-based publicly traded (TSX: AIDX) healthcare-AI company focused on early disease detection and clinical data. Aggressive M&A: acquired Pentavere (2025), VeroSource and BioPharma Services (2024), and ...

Jordan Jacobs, Tomi Poutanen, Maks Volkovs

Founded 2016; enterprise ML (deep learning, generative AI, forecasting, recommenders). Acquired by TD Bank Group in 2018 and now TD's AI centre of excellence based at MaRS, serving 27M+ customers; three-time...

Clinical-NLP AI (DARWEN engine) that turns unstructured clinical text into real-world evidence; works with 6 of the top-10 pharma companies and won the Prix Galien USA 2024 (Best Startup, Digital Health). Ac...

Liran Belenzon, Tom Leung, David Q. Chen, Elvis Wianda

Founded 2015 out of the U of T Creative Destruction Lab. AI platform (ASCEND) that uses text + image ML to accelerate preclinical drug discovery; used by 16 of the top-20 pharma companies (Eli Lilly, Moderna...

Yuanming (Jon) Shu, Jon Kolominsky

Founded 2013. Converts high-resolution imagery into HD vector maps using AI; built HD maps of Toronto for autonomous vehicles (with OVIN/Ontario) and 3D vector maps of Canada's top-100 cities via an C$8M SDT...

Sam Cooper, Oren Kraus

AI drug-discovery company using machine-learning image analysis and single-cell/phenotypic data to target the tumor stroma in solid cancers. ~US$8.7M raised (investors incl. TIAP, AV8 Ventures, CTI Life Scie...

Patricia Thaine, Pieter Luitjens

Founded 2017 by U of T / Vector-affiliated researchers. Privacy infrastructure that detects, redacts and replaces 50+ types of PII across 47+ languages for AI/LLM pipelines. Raised C$10.7M (led by BDC Capita...

Tomi Poutanen, Mara Lederman

Launched 2022 by Layer 6 co-founder Tomi Poutanen and Rotman/CDL's Mara Lederman. Health-AI platform (AIMS) deploying real-time clinical ML in hospitals; first app CHARTWatch predicts patient deterioration. ...

Mike Murchison, David Hariri

Founded 2016 in Toronto (U of Toronto roots); AI-native customer-experience automation platform used by Meta, Shopify, Verizon, Telus and Upwork. Raised a US$130M Series C in 2021 at a US$1.2B+ valuation (Sp...

AI-native customer-service automation platform deploying intelligent chatbots/agents that autonomously resolve high volumes of support inquiries. A Toronto AI unicorn and an early Cohere customer; a leading ...

Benjamin Alarie, Anthony Niblett, Albert Yoon, Brett Janssen

Founded 2015 in Toronto by U of T law professors; generative-AI tax and legal research platform delivering citation-backed answers from authoritative sources (pivoted from a prediction engine to GenAI in 202...

Enterprise LLM / NLP infrastructure company founded by Aidan Gomez, Ivan Zhang, and Nick Frosst (U of T / "Attention Is All You Need" lineage). Has raised ~$1.64B total; secured up to $240M CAD from the Gove...

Hossein Rahnama

Founded 2013 in Toronto (Ryerson/TMU spinout); context-as-a-service / data personalization platform that unifies disparate data sources to power personalized customer experiences, primarily for financial ins...

US firm Forum Ventures established an AI venture studio in Toronto (from 2023), securing ~$21.5M USD (~$30.2M CAD) across two funds to build AI-native B2B SaaS companies — a signal of Toronto's pull as a pla...

Justin LaFayette, Simon Chong, John Berton

Founded 2008; Canada's largest independent VC (~US$5.7B AUM), a growth-equity firm investing in data/AI-driven software (Series B–D, ~US$20–75M checks). Runs an in-house 20+ person AI/ML lab supporting portf...

Web3 gaming technology and analytics platform serving game studios with data, growth, and security tooling. One of Toronto's most visible web3-gaming infrastructure startups.

Noah Waisberg, Alexander Hudek

Founded 2011 in Toronto; machine-learning contract-review and analysis software (legal AI / data extraction), an early legal-AI pioneer. Acquired by Litera in 2021-22; spun off Zuva to serve corporate custom...

Govtech / AI startup bringing AI to the "black box" of government contracting. Raised an $18M USD (~$24.6M CAD) Series A led by Menlo Ventures, closing Q4 2025 — one of the more notable govtech rounds in the...

Jordan Jacobs, Tomi Poutanen, Salim Teja, Aaron Rosenberg

Founded 2017; Toronto-based, AI-only venture firm and the ecosystem's most important local capital source. Early backer of Cohere, Waabi, Untether AI, Signal 1 and Writer. Closed a US$650M early-stage Fund I...

Etai Mizrahi, Andrew McEwen

Founded 2021 in Toronto (YC-backed); AI-powered data catalog / governance, lineage and discovery platform for data teams. Raised ~US$16M (Series A led by Craft Ventures). Acquired by Atlassian in December 20...

Web3 company extending blockchain principles to off-chain, decentralized data management (products include DefraDB and the SourceHub protocol); raised funding from Delphi Ventures. A deep-infrastructure web3...

Stephany Lapierre

Founded ~2014/2015 in Toronto; AI-driven Supplier Data Platform that autonomously enriches supplier/vendor master data across millions of global suppliers for procurement teams. Acquired by Supplier.io in Ap...

Autonomous-driving (self-driving trucks) company founded by U of T professor Raquel Urtasun, using an AI-first "Waabi World" simulation approach. Reported to have reached unicorn status as of January 2026 — ...